RSS Feed for 'Gary Null' show on PRN

Wed Jun 22, 2022 20:04

Videos:

1. The great recycling LIE (what really happens to plastic) (10:44) 2. Is It Game Over? New NASA Report (5:30) 2. You won’t believe what Justin Trudeau’s government just did | Redacted with Clayton Morris (13:26) 3. Neil Oliver – Who pulls the strings – Pandemic Treaty, Wealth & Power? (2:00) 4. He’s EXPOSING the truth in Syria and they don’t like it | Redacted conversation w/ Kevork Almassian (first 10:00) 5. Russian Ruble now best performing currency in the world this year… another example of how US sanctions have failed. 6. Vanessa Beeley and Eva Bartlett are smeared by the Guardian for reporting the truth (3:07) 7. Kim Iversen: Inside The SECRET Bilderberg Meetings Between Spies, War Hawks And World Leaders (9:28) 8. New Rule: The Misinformation Age | Real Time with Bill Maher (HBO) 9. https://theduran.locals.com/post/2311112/title 

10. https://www.youtube.com/watch?v=3maIN4-ZJl8 

 

Strawberry Compound Shown to Protect Against Alzheimer’s, Memory Loss

Salk Institute for Biological Studies, June 16, 2022 

The thought of losing your mind is a frightening one, but one in three Americans die with Alzheimer’s or some other form of dementia. Regardless how frightening the possibility is, the chances of it happening to you aren’t exactly slim, which means prevention should be at the forefront of your mind. A recent study from the Salk Institute for Biological Studies indicates prevention could be as simple as a natural foods diet—rich in fruits (such as strawberries) and vegetables containing something called fisetin.

Fisetin is a flavonol found in strawberries, mangoes, cucumbers, and other vegetables and fruits. Researchers with the Salk Institute found this simple compound can actually reduce the risk of Alzheimer’s in mice, and could be effective in humans as well.

Maher and her team have documented that fisetin has both anti-inflammatory and antioxidant properties in the brain. It is also able to turn on a cellular pathway related to memory function.

The team looked to a type of mouse with mutated genes making them vulnerable to Alzheimer’s. At three months old, the researchers began feeding the mice a diet enriched with fisetin.

Mice who hadn’t received the fisetin began struggling in the mazes at nine months of age, but the fisetin mice performed as well as normal (non-predisposed) mice at both nine and twelve months of age.

Avocados may hold the answer to beating leukemia

University of Waterloo (Canada), June 16, 2022

Rich, creamy, nutritious and now cancer fighting. New research reveals that molecules derived from avocados could be effective in treating a form of cancer.

Professor Paul Spagnuolo from the University of Waterloo has discovered a lipid in avocados that combats acute myeloid leukemia (AML) by targeting the root of the disease – leukemia stem cells. Worldwide, there are few drug treatments available to patients that target leukemia stem cells.

“The stem cell is really the cell that drives the disease,” said Professor Spagnuolo, in Waterloo’s School of Pharmacy. “The stem cell is largely responsible for the disease developing and it’s the reason why so many patients with leukemia relapse. We’ve performed many rounds of testing to determine how this new drug works at a molecular level and confirmed that it targets stem cells selectively, leaving healthy cells unharmed.”

Inability to stand on one leg for 10 seconds in mid to later life linked to near doubling in risk of death Exercise Medicine Clinic-CLINIMEX (Brazil) and University of Eastern Finland, June 21, 2022

The inability to stand on one leg for 10 seconds in mid- to later life is linked to a near doubling in the risk of death from any cause within the next 10 years, finds research published online in the British Journal of Sports Medicine

This simple and safe balance test could be included in routine health checks for older adults, say the researchers.

The researchers wanted to find out whether a balance test might be a reliable indicator of a person’s risk of death from any cause within the next decade, and, as such, might therefore merit inclusion in routine health checks in later life.

Participants were asked to stand on one leg for 10 seconds without any additional support. 

To improve standardization of the test, participants were asked to place the front of the free foot on the back of the opposite lower leg, while keeping their arms by their sides and their gaze fixed straight ahead. Up to three attempts on either foot were permitted.

In all, around 1 in 5 (20.5%; 348) participants failed to pass the test. The inability to do so rose in tandem with age, more or less doubling at subsequent 5 year intervals from the age of 51-55 onwards. 

The proportions of those unable to stand on one leg for 10 seconds were: nearly 5% among 51-55 year-olds; 8% among 56-60 year-olds; just under 18% among 61-65 year-olds; and just under 37% among 66-70 year-olds. 

More than half (around 54%) of those aged 71-75 were unable to complete the test. In other words, people in this age group were more than 11 times as likely to fail the test as those just 20 years younger.

During an average monitoring period of 7 years, 123 (7%) people died: cancer (32%); cardiovascular disease (30%); respiratory disease (9%); and COVID-19 complications (7%). The proportion of deaths among those who failed the test was significantly higher: 17.5% vs. 4.5%, reflecting an absolute difference of just under 13%.

Anxious Children have Bigger “Fear Centers” in the Brain

Stanford University School of Medicine, June 16, 2022

The amygdala is a key “fear center” in the brain. Alterations in the development of the amygdala during childhood may have an important influence on the development of anxiety problems, reports a new study in the current issue of Biological Psychiatry.



Researchers at the Stanford University School of Medicine recruited 76 children, 7 to 9 years of age, a period when anxiety-related traits and symptoms can first be reliably identified. 

The researchers found that children with high levels of anxiety had enlarged amygdala volume and increased connectivity with other brain regions responsible for attention, emotion perception, and regulation, compared to children with low levels of anxiety. They also developed an equation that reliably predicted the children’s anxiety level from the MRI measurements of amygdala volume and amygdala functional connectivity.

The most affected region was the basolateral portion of the amygdala, a subregion of the amygdala implicated in fear learning and the processing of emotion-related information.



Our study represents an important step in characterizing altered brain systems and developing predictive biomarkers in the identification for young children at risk for anxiety disorders,” Qin said. 

New research: Olive oil compound destroys cancer cells in 30 minutes

Rutgers University & Hunter College, June 12, 2022

 Oleocanthal, a polyphenolic, therapeutic compound found in olive oil is the subject of a new anti-cancer study performed by nutritional science and cancer biology researchers with The School of Environmental and Biological Sciences at Rutgers and Hunter’s College in New York City.

Programmed cell death, known as apoptosis takes approximately 16-24 hours. Dynamic new research just published in the Journal of Molecular and Cellular Oncology blew scientists away – when exposed to oleocanthal, a polyphenol compound found in olive oil, cancerous cells died within 30 minutes to an hour. While researchers previously understood that compounds in olive oil were capable of killing cancer cells, until now, such short apoptosis had not been observed.

Even more fascinating was when the team looked closely to surmise why apoptosis was occurring under such swift circumstances – they discovered that cancer cells were being killed by their own enzymes. And, not only one isolated type of cancerous cell, but all of the cancerous cells they were examining.

Unlike chemotherapeutic pharmaceuticals that devastate healthy cellular activity, the therapeutic polyphenolic compound found in olive oil kills cancer while maintaining vitality among healthy cells. As Paul Breslin, one of the study’s authors at Rutgers noted, while cancerous cells died, healthy cells were not harmed, but rather the oleocanthal “put them to sleep.” The lifecycle of healthy cells was only temporarily affected in this way, without any negative observations and in approximately 24 hours, the healthy cells resumed their life cycle. 

Sports, not screens: The key to happier, healthier children

University of South Australia, June 21, 2022

Whether it’s sports practice, music lessons or a casual catch up with friends, when children are involved in after-school activities, they’re more likely to feel happier and healthier than their counterparts who are glued to a screen.

In a new study conducted by the University of South Australia, researchers found that children’s well-being is heightened when they participate in extra-curricular activities, yet lowered when they spent time on social media or playing video games.

Published in BMC Pediatrics, the study analyzed data from 61,759 school students in years 4 to 9, assessing the average number of days per week children participated in after-school activities (3–6pm), and measure these against well-being factors—happiness, sadness, worry, engagement, perseverance, optimism, emotion regulation, and life satisfaction.

It found that most students watched TV about four days of the school week and spent time on social media about three days of the week.

Our study highlights how some out-of-school activities can boost children’s well-being, while others—particularly screens—can chip away at their mental and physical health. “Screens are a massive distraction for children of all ages. And whether children are gaming, watching TV or on social media, there’s something about all screens that’s damaging to their well-being.

Students in lower socio-economic backgrounds who frequently played sports were 15% more likely to be optimistic, 14% more likely to be happy and satisfied with their life, and 10% more likely to be able to regulate their emotions.

Conversely, children who played video games and used social media almost always had lower levels of well-being: up to 9% less likely to be happy, up to 8% to be less optimism and 11% to be more likely to give up on things.

Videos:

1. The great recycling LIE (what really happens to plastic) (10:44) 2. Is It Game Over? New NASA Report (5:30) 2. You won’t believe what Justin Trudeau’s government just did | Redacted with Clayton Morris (13:26) 3. Neil Oliver – Who pulls the strings – Pandemic Treaty, Wealth & Power? (2:00) 4. He’s EXPOSING the truth in Syria and they don’t like it | Redacted conversation w/ Kevork Almassian (first 10:00) 5. Russian Ruble now best performing currency in the world this year… another example of how US sanctions have failed. 6. Vanessa Beeley and Eva Bartlett are smeared by the Guardian for reporting the truth (3:07) 7. Kim Iversen: Inside The SECRET Bilderberg Meetings Between Spies, War Hawks And World Leaders (9:28) 8. New Rule: The Misinformation Age | Real Time with Bill Maher (HBO) 9. https://theduran.locals.com/post/2311112/title 

10. https://www.youtube.com/watch?v=3maIN4-ZJl8 

 

Strawberry Compound Shown to Protect Against Alzheimer’s, Memory Loss

Salk Institute for Biological Studies, June 16, 2022 

The thought of losing your mind is a frightening one, but one in three Americans die with Alzheimer’s or some other form of dementia. Regardless how frightening the possibility is, the chances of it happening to you aren’t exactly slim, which means prevention should be at the forefront of your mind. A recent study from the Salk Institute for Biological Studies indicates prevention could be as simple as a natural foods diet—rich in fruits (such as strawberries) and vegetables containing something called fisetin.

Fisetin is a flavonol found in strawberries, mangoes, cucumbers, and other vegetables and fruits. Researchers with the Salk Institute found this simple compound can actually reduce the risk of Alzheimer’s in mice, and could be effective in humans as well.

Maher and her team have documented that fisetin has both anti-inflammatory and antioxidant properties in the brain. It is also able to turn on a cellular pathway related to memory function.

The team looked to a type of mouse with mutated genes making them vulnerable to Alzheimer’s. At three months old, the researchers began feeding the mice a diet enriched with fisetin.

Mice who hadn’t received the fisetin began struggling in the mazes at nine months of age, but the fisetin mice performed as well as normal (non-predisposed) mice at both nine and twelve months of age.

Avocados may hold the answer to beating leukemia

University of Waterloo (Canada), June 16, 2022

Rich, creamy, nutritious and now cancer fighting. New research reveals that molecules derived from avocados could be effective in treating a form of cancer.

Professor Paul Spagnuolo from the University of Waterloo has discovered a lipid in avocados that combats acute myeloid leukemia (AML) by targeting the root of the disease – leukemia stem cells. Worldwide, there are few drug treatments available to patients that target leukemia stem cells.

“The stem cell is really the cell that drives the disease,” said Professor Spagnuolo, in Waterloo’s School of Pharmacy. “The stem cell is largely responsible for the disease developing and it’s the reason why so many patients with leukemia relapse. We’ve performed many rounds of testing to determine how this new drug works at a molecular level and confirmed that it targets stem cells selectively, leaving healthy cells unharmed.”

Inability to stand on one leg for 10 seconds in mid to later life linked to near doubling in risk of death Exercise Medicine Clinic-CLINIMEX (Brazil) and University of Eastern Finland, June 21, 2022

The inability to stand on one leg for 10 seconds in mid- to later life is linked to a near doubling in the risk of death from any cause within the next 10 years, finds research published online in the British Journal of Sports Medicine

This simple and safe balance test could be included in routine health checks for older adults, say the researchers.

The researchers wanted to find out whether a balance test might be a reliable indicator of a person’s risk of death from any cause within the next decade, and, as such, might therefore merit inclusion in routine health checks in later life.

Participants were asked to stand on one leg for 10 seconds without any additional support. 

To improve standardization of the test, participants were asked to place the front of the free foot on the back of the opposite lower leg, while keeping their arms by their sides and their gaze fixed straight ahead. Up to three attempts on either foot were permitted.

In all, around 1 in 5 (20.5%; 348) participants failed to pass the test. The inability to do so rose in tandem with age, more or less doubling at subsequent 5 year intervals from the age of 51-55 onwards. 

The proportions of those unable to stand on one leg for 10 seconds were: nearly 5% among 51-55 year-olds; 8% among 56-60 year-olds; just under 18% among 61-65 year-olds; and just under 37% among 66-70 year-olds. 

More than half (around 54%) of those aged 71-75 were unable to complete the test. In other words, people in this age group were more than 11 times as likely to fail the test as those just 20 years younger.

During an average monitoring period of 7 years, 123 (7%) people died: cancer (32%); cardiovascular disease (30%); respiratory disease (9%); and COVID-19 complications (7%). The proportion of deaths among those who failed the test was significantly higher: 17.5% vs. 4.5%, reflecting an absolute difference of just under 13%.

Anxious Children have Bigger “Fear Centers” in the Brain

Stanford University School of Medicine, June 16, 2022

The amygdala is a key “fear center” in the brain. Alterations in the development of the amygdala during childhood may have an important influence on the development of anxiety problems, reports a new study in the current issue of Biological Psychiatry.



Researchers at the Stanford University School of Medicine recruited 76 children, 7 to 9 years of age, a period when anxiety-related traits and symptoms can first be reliably identified. 

The researchers found that children with high levels of anxiety had enlarged amygdala volume and increased connectivity with other brain regions responsible for attention, emotion perception, and regulation, compared to children with low levels of anxiety. They also developed an equation that reliably predicted the children’s anxiety level from the MRI measurements of amygdala volume and amygdala functional connectivity.

The most affected region was the basolateral portion of the amygdala, a subregion of the amygdala implicated in fear learning and the processing of emotion-related information.



Our study represents an important step in characterizing altered brain systems and developing predictive biomarkers in the identification for young children at risk for anxiety disorders,” Qin said. 

New research: Olive oil compound destroys cancer cells in 30 minutes

Rutgers University & Hunter College, June 12, 2022

 Oleocanthal, a polyphenolic, therapeutic compound found in olive oil is the subject of a new anti-cancer study performed by nutritional science and cancer biology researchers with The School of Environmental and Biological Sciences at Rutgers and Hunter’s College in New York City.

Programmed cell death, known as apoptosis takes approximately 16-24 hours. Dynamic new research just published in the Journal of Molecular and Cellular Oncology blew scientists away – when exposed to oleocanthal, a polyphenol compound found in olive oil, cancerous cells died within 30 minutes to an hour. While researchers previously understood that compounds in olive oil were capable of killing cancer cells, until now, such short apoptosis had not been observed.

Even more fascinating was when the team looked closely to surmise why apoptosis was occurring under such swift circumstances – they discovered that cancer cells were being killed by their own enzymes. And, not only one isolated type of cancerous cell, but all of the cancerous cells they were examining.

Unlike chemotherapeutic pharmaceuticals that devastate healthy cellular activity, the therapeutic polyphenolic compound found in olive oil kills cancer while maintaining vitality among healthy cells. As Paul Breslin, one of the study’s authors at Rutgers noted, while cancerous cells died, healthy cells were not harmed, but rather the oleocanthal “put them to sleep.” The lifecycle of healthy cells was only temporarily affected in this way, without any negative observations and in approximately 24 hours, the healthy cells resumed their life cycle. 

Sports, not screens: The key to happier, healthier children

University of South Australia, June 21, 2022

Whether it’s sports practice, music lessons or a casual catch up with friends, when children are involved in after-school activities, they’re more likely to feel happier and healthier than their counterparts who are glued to a screen.

In a new study conducted by the University of South Australia, researchers found that children’s well-being is heightened when they participate in extra-curricular activities, yet lowered when they spent time on social media or playing video games.

Published in BMC Pediatrics, the study analyzed data from 61,759 school students in years 4 to 9, assessing the average number of days per week children participated in after-school activities (3–6pm), and measure these against well-being factors—happiness, sadness, worry, engagement, perseverance, optimism, emotion regulation, and life satisfaction.

It found that most students watched TV about four days of the school week and spent time on social media about three days of the week.

Our study highlights how some out-of-school activities can boost children’s well-being, while others—particularly screens—can chip away at their mental and physical health. “Screens are a massive distraction for children of all ages. And whether children are gaming, watching TV or on social media, there’s something about all screens that’s damaging to their well-being.

Students in lower socio-economic backgrounds who frequently played sports were 15% more likely to be optimistic, 14% more likely to be happy and satisfied with their life, and 10% more likely to be able to regulate their emotions.

Conversely, children who played video games and used social media almost always had lower levels of well-being: up to 9% less likely to be happy, up to 8% to be less optimism and 11% to be more likely to give up on things.

Tue Jun 21, 2022 19:29

Consumption of berries, fruits and vegetables and mortality among 10,000 Men Followed for four decades

Folkhalsan Research Center (Norway), June 17, 2022

Investigators from Folkhalsan Research Center in Norway found that consumption of berries, fruits and vegetables and mortality among 10,000 Norwegian men followed for four decades

"The association between vegetable and fruit consumption and risk of cancer and cardiovascular disease (CVD) has been investigated by several studies, whereas fewer studies have examined consumption of vegetables and fruits in relation to all-cause mortality. Studies on berries, a rich source of antioxidants, are rare."

"The purpose of the current study was to examine the association between intake of vegetables, fruits and berries (together and separately) and the risk of all-cause mortality and cause-specific mortality due to cancer and CVD and subtypes of these, in a cohort with very long follow-up. We used data from a population-based prospective Norwegian cohort study of 10,000 men. 

Men who in total consumed vegetables, fruit and berries more than 27 times per month had an 8-10 % reduced risk of all-cause mortality compared with men with a lower consumption. They also had a 20 % reduced risk of stroke mortality. Consumption of fruit was inversely related to overall cancer mortality, with hazard rate ratios of 0.94, 0.84 and 0.79 in the second, third and firth quartile, respectively, compared with the first quartile."

According to the news editors, the research concluded: "Increased consumption of vegetables, fruits and berries was associated with a delayed risk of all-cause mortality and of mortality due to cancer and stroke."

 

 

 

UA researchers discover component of cinnamon prevents colorectal cancer in mice

University of Arizona, June 15, 2022

Research conducted at the University of Arizona College of Pharmacy and the UA Cancer Center indicates that a compound derived from cinnamon is a potent inhibitor of colorectal cancer.

Georg Wondrak, Ph.D., recently completed a study in which they proved that adding cinnamaldehyde, the compound that gives cinnamon its distinctive flavor and smell, to the diet of mice protected the mice against colorectal cancer. In response to cinnamaldehyde, the animals' cells had acquired the ability to protect themselves against exposure to a carcinogen through detoxification and repair.

Given cinnamon's important status as the third-most-consumed spice in the world,' Wondrak adds, 'there's relatively little research on its potential health benefits. If we can ascertain the positive effects of cinnamon, we would like to leverage this opportunity to potentially improve the health of people around the globe.'

Drs. Wondrak and Zhang's study, 'Nrf2-dependent suppression of azoxymethane/dextrane sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde,' has been published in Cancer Prevention Research later this spring.

 

 

    Lean tissue benefit of protein supplementation affirmed

Universidade Federal do Rio Grande do Sul (Brazil), June 17, 2022. 

A “systematic review of systematic reviews” published  in Sports Medicine showed that the addition of protein supplementation to resistance training is associated with a greater increase in lean body mass (body mass minus fat mass) in comparison with resistance training alone. 

Researchers in Brazil selected 46 studies in the meta-analyses involved a total of 2,925 men and women over 50 years of age. Supplemented groups received 12 to 40 grams of protein or 3 to 10 grams of amino acids while the control groups received a placebo or no supplementation.

Among the 4 meta-analyses that evaluated lean body mass, 3 found a significant increase in association with resistance training plus protein supplementation compared to resistance training without supplementation. There was also a significant benefit for protein supplementation combined with training on muscle mass alone.

“It is possible to conclude that protein supplementation associated with resistance training induces greater increases in lean body mass compared with resistance training alone in older participants. In addition, it is suggested that the effect of protein supplementation on lean body mass is extended to the increase in muscle mass, while no additional effect of protein supplementation was observed on muscle strength in older adults.”

      Study shows inhaled toxic particles take direct route from lungs to brain

University of Birmingham, June 20, 2022

Breathing in polluted air could lead to toxic particles being transported from lungs to brain, via the bloodstream—potentially contributing to brain disorders and neurological damage, a new study reveals.

Scientists have discovered a possible direct pathway used by various inhaled fine particles through blood circulation with indications that, once there, the particles stay longer in the brain than in other main metabolic organs.

The scientists revealed they had found various fine particles in human cerebrospinal fluids taken from patients who had experienced brain disorders—uncovering a process which may result in toxic particulate substances ending up in the brain.

"The data suggests that up to eight times the number of fine particles may reach the brain by traveling, via the bloodstream, from the lungs than pass directly via the nose—adding new evidence on the relationship between air pollution and detrimental effects of such particles on the brain."

 

Turmeric: A Wellness Promoting Tonic At Low Doses, Research Reveals

Ohio State University, June 12, 2022

A study published in the Nutrition Journal   holds great interest among those on the fence about using dietary supplements to improve the quality and perhaps length of their lives, but for which clinical proof is lacking.

The study was conducted in healthy middle aged people (40–60 years old) with a low dose of curcumin (80 mg/day) in a fat soluble (lipidated) form.  Two groups of 19 subjects were given either curcumin or placebo for 4 weeks. Blood and saliva samples were taken before and after the 4 weeks and analyzed for the following blood and saliva measures relevant to health promotion The positive results were reported as follows:

  • Curcumin lowered triglycerides, but not cholesterol (note: lowering cholesterol may harm human health).
  • Curcumin increased plasma contents of nitric oxide, a molecule that can work against high blood pressure, as well as lowering plasma concentrations of sICAM, a molecule linked to atherosclerosis.
  • Curcumin raised plasma myeloperoxidase concentrations, without raising C-reactive protein and ceruloplasmin values – a sign of normal and inflammation-related neutrophil function.
  • Curcumin reduced salivary amylase activities, which are an indicator of sympathetic nervous system stress.
  • Curcumin raised salivary radical scavenging capacities, an indicator of reduced oxidative stress.·
  • Curcumin reduced plasma contents of beta amyloid protein, a marker for brain aging and Alzheimer’s disease.
  • Curcumin reduced ALT liver enzyme activities, a marker for liver injury.

 

Natural cocoa consumption: Potential to reduce atherogenic factors?

University of North Texas, June 17, 2022

According to news reporting in University of North Texas, research stated, "Short-term consumption of flavanol-rich cocoa has been demonstrated to improve various facets of vascular health. The purpose of the present study was to determine the effect of 4 weeks of natural cocoa consumption on selected cardiovascular disease (CVD) biomarkers in young (19-35 years) women of differing body mass indices (BMI)."

"Subjects (n=24) consumed a natural cocoa-containing product (12.7 g natural cocoa, 148 kcal/serving) or an isocaloric cocoa-free placebo daily for 4 weeks in a random, double-blind manner with a 2-week washout period between treatment arms. 

Natural cocoa consumption resulted in a significant decrease in haptoglobin, EMP concentration and monocyte CD62L in obese compared to overweight and normal-weight subjects. Natural cocoa consumption regardless of BMI group was associated with an 18% increase in high-density lipoprotein and a 60% decrease in EMPs. Also, obese subjects experienced a 21% decrease in haptoglobin and a 24% decrease in monocyte CD62L expression in following 4 weeks of natural cocoa consumption. Collectively, these findings indicate that acute natural cocoa consumption was associated with decreased obesity-related disease risk."

Consumption of berries, fruits and vegetables and mortality among 10,000 Men Followed for four decades

Folkhalsan Research Center (Norway), June 17, 2022

Investigators from Folkhalsan Research Center in Norway found that consumption of berries, fruits and vegetables and mortality among 10,000 Norwegian men followed for four decades

"The association between vegetable and fruit consumption and risk of cancer and cardiovascular disease (CVD) has been investigated by several studies, whereas fewer studies have examined consumption of vegetables and fruits in relation to all-cause mortality. Studies on berries, a rich source of antioxidants, are rare."

"The purpose of the current study was to examine the association between intake of vegetables, fruits and berries (together and separately) and the risk of all-cause mortality and cause-specific mortality due to cancer and CVD and subtypes of these, in a cohort with very long follow-up. We used data from a population-based prospective Norwegian cohort study of 10,000 men. 

Men who in total consumed vegetables, fruit and berries more than 27 times per month had an 8-10 % reduced risk of all-cause mortality compared with men with a lower consumption. They also had a 20 % reduced risk of stroke mortality. Consumption of fruit was inversely related to overall cancer mortality, with hazard rate ratios of 0.94, 0.84 and 0.79 in the second, third and firth quartile, respectively, compared with the first quartile."

According to the news editors, the research concluded: "Increased consumption of vegetables, fruits and berries was associated with a delayed risk of all-cause mortality and of mortality due to cancer and stroke."

 

 

 

UA researchers discover component of cinnamon prevents colorectal cancer in mice

University of Arizona, June 15, 2022

Research conducted at the University of Arizona College of Pharmacy and the UA Cancer Center indicates that a compound derived from cinnamon is a potent inhibitor of colorectal cancer.

Georg Wondrak, Ph.D., recently completed a study in which they proved that adding cinnamaldehyde, the compound that gives cinnamon its distinctive flavor and smell, to the diet of mice protected the mice against colorectal cancer. In response to cinnamaldehyde, the animals' cells had acquired the ability to protect themselves against exposure to a carcinogen through detoxification and repair.

Given cinnamon's important status as the third-most-consumed spice in the world,' Wondrak adds, 'there's relatively little research on its potential health benefits. If we can ascertain the positive effects of cinnamon, we would like to leverage this opportunity to potentially improve the health of people around the globe.'

Drs. Wondrak and Zhang's study, 'Nrf2-dependent suppression of azoxymethane/dextrane sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde,' has been published in Cancer Prevention Research later this spring.

 

 

    Lean tissue benefit of protein supplementation affirmed

Universidade Federal do Rio Grande do Sul (Brazil), June 17, 2022. 

A “systematic review of systematic reviews” published  in Sports Medicine showed that the addition of protein supplementation to resistance training is associated with a greater increase in lean body mass (body mass minus fat mass) in comparison with resistance training alone. 

Researchers in Brazil selected 46 studies in the meta-analyses involved a total of 2,925 men and women over 50 years of age. Supplemented groups received 12 to 40 grams of protein or 3 to 10 grams of amino acids while the control groups received a placebo or no supplementation.

Among the 4 meta-analyses that evaluated lean body mass, 3 found a significant increase in association with resistance training plus protein supplementation compared to resistance training without supplementation. There was also a significant benefit for protein supplementation combined with training on muscle mass alone.

“It is possible to conclude that protein supplementation associated with resistance training induces greater increases in lean body mass compared with resistance training alone in older participants. In addition, it is suggested that the effect of protein supplementation on lean body mass is extended to the increase in muscle mass, while no additional effect of protein supplementation was observed on muscle strength in older adults.”

      Study shows inhaled toxic particles take direct route from lungs to brain

University of Birmingham, June 20, 2022

Breathing in polluted air could lead to toxic particles being transported from lungs to brain, via the bloodstream—potentially contributing to brain disorders and neurological damage, a new study reveals.

Scientists have discovered a possible direct pathway used by various inhaled fine particles through blood circulation with indications that, once there, the particles stay longer in the brain than in other main metabolic organs.

The scientists revealed they had found various fine particles in human cerebrospinal fluids taken from patients who had experienced brain disorders—uncovering a process which may result in toxic particulate substances ending up in the brain.

"The data suggests that up to eight times the number of fine particles may reach the brain by traveling, via the bloodstream, from the lungs than pass directly via the nose—adding new evidence on the relationship between air pollution and detrimental effects of such particles on the brain."

 

Turmeric: A Wellness Promoting Tonic At Low Doses, Research Reveals

Ohio State University, June 12, 2022

A study published in the Nutrition Journal   holds great interest among those on the fence about using dietary supplements to improve the quality and perhaps length of their lives, but for which clinical proof is lacking.

The study was conducted in healthy middle aged people (40–60 years old) with a low dose of curcumin (80 mg/day) in a fat soluble (lipidated) form.  Two groups of 19 subjects were given either curcumin or placebo for 4 weeks. Blood and saliva samples were taken before and after the 4 weeks and analyzed for the following blood and saliva measures relevant to health promotion The positive results were reported as follows:

  • Curcumin lowered triglycerides, but not cholesterol (note: lowering cholesterol may harm human health).
  • Curcumin increased plasma contents of nitric oxide, a molecule that can work against high blood pressure, as well as lowering plasma concentrations of sICAM, a molecule linked to atherosclerosis.
  • Curcumin raised plasma myeloperoxidase concentrations, without raising C-reactive protein and ceruloplasmin values – a sign of normal and inflammation-related neutrophil function.
  • Curcumin reduced salivary amylase activities, which are an indicator of sympathetic nervous system stress.
  • Curcumin raised salivary radical scavenging capacities, an indicator of reduced oxidative stress.·
  • Curcumin reduced plasma contents of beta amyloid protein, a marker for brain aging and Alzheimer’s disease.
  • Curcumin reduced ALT liver enzyme activities, a marker for liver injury.

 

Natural cocoa consumption: Potential to reduce atherogenic factors?

University of North Texas, June 17, 2022

According to news reporting in University of North Texas, research stated, "Short-term consumption of flavanol-rich cocoa has been demonstrated to improve various facets of vascular health. The purpose of the present study was to determine the effect of 4 weeks of natural cocoa consumption on selected cardiovascular disease (CVD) biomarkers in young (19-35 years) women of differing body mass indices (BMI)."

"Subjects (n=24) consumed a natural cocoa-containing product (12.7 g natural cocoa, 148 kcal/serving) or an isocaloric cocoa-free placebo daily for 4 weeks in a random, double-blind manner with a 2-week washout period between treatment arms. 

Natural cocoa consumption resulted in a significant decrease in haptoglobin, EMP concentration and monocyte CD62L in obese compared to overweight and normal-weight subjects. Natural cocoa consumption regardless of BMI group was associated with an 18% increase in high-density lipoprotein and a 60% decrease in EMPs. Also, obese subjects experienced a 21% decrease in haptoglobin and a 24% decrease in monocyte CD62L expression in following 4 weeks of natural cocoa consumption. Collectively, these findings indicate that acute natural cocoa consumption was associated with decreased obesity-related disease risk."

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